Fractional Leadership for Life Sciences

Fractional C-suite leadership and AI-powered execution for life sciences companies at critical inflection points.

Operait helps healthcare, biotech, pharma, medtech, and regulated-market companies move faster through fundraising, BD, M&A, market entry, launches, turnarounds, and AI transformation — without the cost or delay of a full-time executive hire.

Led by Jonathan Berlent — senior operator with 20+ years across healthcare, life sciences, regulated markets. Expertise: business growth, operations, M&A, business development.

Jonathan's Operating Credentials
Transaction Experience
$1B+
Led a $1.5B acquisition for a publicly traded diagnostics company through rigorous portfolio analysis and deal structuring.
Franchise Built
$50M+
Scaled specialty pharma franchise from acquisition through FDA approval and US commercial launch.
Partnerships Closed
$100M+
Closed $100M+ in licensing, distribution, and partnership transactions across branded, generic, and biologic product lines.
Years of Experience
20+
Operating executive across biotech, pharma, regenerative medicine, and clinical-stage development — clinical through commercial.

When to Call Operait

Fundraising Momentum

You're closing a Series A / B / C, and you need an experienced operator to refine the narrative, stress-test your assumptions, and signal momentum to investors.

M&A or Partnership Execution

You're evaluating a strategic acquisition, structuring a BD deal, or entering a new partnership. You need experienced deal architecture and cross-functional orchestration.

Market Entry or Launch

You're entering a new market, launching a product, or scaling commercial infrastructure. You need a fractional executive to build and execute the playbook.

Operational Turnaround

Your business is underperforming. You need diagnostic clarity on constraints, a realistic recovery plan, and hands-on execution to restore momentum.

AI & Digital Transformation

You're integrating AI into your business model — operations, customer experience, or strategy. You need an advisor who understands both AI and regulated markets.

Board or Advisory Role

You need external strategic counsel, quarterly advisory sprints, or a trusted sounding board for major decisions. We work with boards and investors, not just founders.

BIOTECH • PHARMA • MEDTECH • DIGITAL HEALTH • M&A • FUNDRAISING • BOARD ADVISORY • AI STRATEGY • BIOTECH • PHARMA • MEDTECH • DIGITAL HEALTH • M&A • FUNDRAISING • BOARD ADVISORY • AI STRATEGY •

Three Ways Operait Helps

We diagnose constraints, build executable clarity, and orchestrate execution across product, commercial, pipeline, and partnerships. Strategic advisor with operating authority.

Strategy Sprint

Intensive 4-week engagement: Diagnosis of growth constraints, clear strategy framework, executable roadmap, and immediate tactical execution. Ideal for founders, boards, and capital-raising moments.

Operational Partnership

Fractional President, COO, or SVP role: Ongoing leadership and execution across capital strategy, portfolio decisions, and team coordination. Report directly to CEO or board. Scale from part-time to full-time.

Board & Advisory

Quarterly advisory sprints or standing board role: Strategic counsel on capital, partnerships, market opportunity, and operational risk. Deep engagement without full-time employment.

AI-Augmented Execution

Advanced Analytics

3xAI

AI-powered operational acceleration for biotech, pharma, and regulated markets. Process optimization, market intelligence, deal analysis, and board materials — delivered fast and at lower cost than traditional consulting.

Learn about 3xAI →
Acquisition Strategy

TENxAI

AI-augmented acquisition and integration platform for biotech and pharma companies. Portfolio analysis, target identification, valuation modeling, and post-acquisition optimization.

Learn about TENxAI →

Outcomes We Deliver

Capital Clarity

Refined fundraising narrative, investor pitch, and capital strategy. Closed capital faster with higher valuations and better terms.

Portfolio Decisions

Clear asset prioritization, deprioritization roadmap, and pipeline strategy. Kill underperforming assets faster; double down on winners.

Operational Momentum

Cross-functional alignment, team clarity, execution velocity. Move faster. Reduce friction. Ship results.

M&A Execution

Strategic deal sourcing, target evaluation, deal architecture, and post-close integration. Closed transactions. Built teams. Created value.

Commercial Launch

Go-to-market strategy, market entry playbook, team building, and launch execution. Scaled revenue. Hired teams. Built infrastructure.

Board Confidence

External perspective. Strategic counsel. De-risking major decisions. Trusted advisor to boards and founders.

About Jonathan Berlent

Operating Executive & Strategic Advisor | Biotech & Specialty Pharma | Clinical-Stage to Commercial

Jonathan is a senior operator with 20+ years building and scaling biotech, pharma, and regulated-market businesses. Trusted by boards, founders, and investors to diagnose growth constraints, execute operational recovery, and close strategic partnerships and acquisitions.

What He Brings: Clinical development strategy, regulatory pathway optimization, commercial infrastructure build, M&A deal architecture, business development strategy, capital formation, and team leadership across clinical, manufacturing, commercial, and investor-facing functions.

Recent Work: SVP Strategy at Merakris Therapeutics (regenerative medicine, clinical-stage allograft + Phase 2b biologic); President of Sentiss Pharmaceuticals North America (sterile ophthalmic manufacturing + M&A); advisor to biotech founders, boards, and institutional investors on portfolio strategy, capital formation, and partnership execution.

Education: NYU Stern MBA; University of Michigan (Economics). Email: jonathan@operait.co

Where We Operate

Growth Stage (Small to Mid-Market)

Life Sciences

  • Branded Biotech
  • Specialty Pharma
  • Generic Pharma
  • Medtech
  • Digital Health

Operating Companies

  • Industrial
  • CPG
  • Food & Agriculture
  • Technology
  • Consumer
  • Other Markets

Scale Stage (Large Company)

Life Sciences

  • Pharmaceutical
  • Capital Markets
  • M&A | BD
  • Digital Health
  • PE/VC-Backed Healthcare

Operating Companies

  • Industrial
  • CPG
  • Food & Agriculture
  • Technology
  • Consumer
  • Other Markets

The Operait Advantage

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